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A World Without Kidney Diseases

ASN represents more than 21,000 kidney health professionals working to help people with kidney diseases and their families. Comprised of all of ASN's focus areas, the ASN Alliance for Kidney Health allows the society to continue its growth and work towards the goal of a world without kidney diseases.

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Kidney Week On-Demand™ Is Now Available

Kidney Week On-Demand™ Is Now Available

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Promoting Person-Directed Outcomes-Oriented Care

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Discover the latest strategies and advancements in obesity management and kidney diseases with Kidney Health Guidance, ASN's comprehensive new clinical resource.

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Latest nephSAP: October 2024

The latest Nephrology Self-Assessment Program (nephSAP) issue, Volume 23: Issue 4 (Oct 2024): Chronic Kidney Disease is now available online.

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Roadmap for Advancing Awareness, Genetic Testing, and Clinical Testing of APOL1 Kidney Disease

APOL1 kidney disease (APOL1 KD) is a driving force behind health disparities in chronic kidney disease (CKD) characterized by worse health outcomes for those of African ancestry...
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AKINow Journal Club: Intravenous Amino Acids for Kidney Protection

Acute kidney injury (AKI) is a serious and common complication of cardiac surgery. Intravenous amino acids increase kidney perfusion and recruit renal functional reserve. Howeve...
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Toward a Restrictive Use of Plasma Exchanges in Thrombotic Microangiopathies

JASN | Wednesday, October 16

Perspectives on Long-Term Follow-Up Among Living Kidney Donors

CJASN | Tuesday, October 15

Global Perspective on Challenges and Potential Solutions to Increasing Peritoneal Dialysis in Egypt

Kidney360 | Thursday, September 26

Targeting CD38 in Acute Antibody-Mediated Rejection: A New Hope for Kidney Transplant Recipients?

Kidney News | Monday, October 7
RE: Patient with fabry disease and also possible minimal change 3 hours ago

Very rare to have Fabry's Disease and MCD conurrently, but I found 2 suchcase reports in the published literature. Shows how the ASN Communities te...

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RE: Persistant Hemoptysis In Anti-GBM 6 hours ago

Good question- in my opinion- the goal of therapy of Lisinopril online anti-GBM disease is to reduce the level of anti-GBM to undetectable levels, as quickly as poss...

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RE: Dialysis Question 6 hours ago

Thanks --------------------------------- Muhammad Soobadar MBChB UK ---------------------------------

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RE: Persistant Hemoptysis In Anti-GBM 7 hours ago

Thank you prof Glassock I have a question looks like basic question But actually I don’t know Our lab result by ELISA Normal Range (<20 U/mL) r...

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RE: Clinical Practice Questions 9 hours ago

CMV pcr positive and treated with valganciclovir and now 2 cmv pcr negative . Due to the fact that there is no final biopsy report , pt creatinine...

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RE: Persistant Hemoptysis In Anti-GBM 10 hours ago

If the serum antiGBM is positive ( using a sensitive commercial ELISA for IgG aGBM) even at very low levels and the patient has symptomatic hemopty...

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RE: Persistant Hemoptysis In Anti-GBM 13 hours ago

Echo EF 65% no abnormalities Patient not dyspneic, not volume overload I think smoking is the cause I found case report about smoking associate...

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RE: Persistant Hemoptysis In Anti-GBM 13 hours ago

I guess my point is that tissue bound anti-GBM antibody can persist for some period (? weeks) after the serum antibody have declined to undetectabl...

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RE: Persistant Hemoptysis In Anti-GBM 13 hours ago

A single breath CO uptake test will distinguish volume expansion pulmonary edema and intra-alveolar hemorrhage. Has an Echocardiogram been done? ...

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RE: Persistant Hemoptysis In Anti-GBM 16 hours ago

Also to check carefully the volume status. Many patients do develop hemoptysis secondary to pulmonary edema as a result of renal dysfunction. A nor...

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RE: Clinical Practice Questions 17 hours ago

If CMV PCR was never positive then CMV GN not present -so was it elevated and high high before treatment ? ------------------------------ [Mark] ...

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RE: Management In ADTKD 1 day ago

Perhaps we can lobby hospitals and companies to provide free service based on need. ------------------------------ Ashraf El-Meanawy , MD, MS, P...

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RE: Persistant Hemoptysis In Anti-GBM 1 day ago

Dr. Friedman is quite correct to raise the issue if a procoagulant deficiency state (primarily Fibrinogen) following extensive PLEX with albumin on...

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RE: Steroid dependent FSGS with "tip lesion" 1 day ago

Thank you Dr Rodby ------------------------------ Asjad Sardar MD SOUTHWEST KIDNEY INSTITUTE Tucson AZ (646) 236-8170 ---------------------------...

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RE: Steroid dependent FSGS with "tip lesion" 1 day ago

Thank you so much for your input Dr Glassock. He is a caucasian ------------------------------ Asjad Sardar MD SOUTHWEST KIDNEY INSTITUTE Tucs...

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RE: Patient with fabry disease and also possible minimal change 1 day ago

Just out of curiosity, what was her GLA gene variant, eg E66Q, N215S…? --------------------------------- Oded Friedman ---------------------------...

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RE: Persistant Hemoptysis In Anti-GBM 1 day ago

If albumin was used as RF, what are his INR, PTT & fibrinogen? --------------------------------- Oded Friedman ---------------------------------

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RE: Management In ADTKD 1 day ago

Dr Bleyer and rest of respected members thanks a lot Dr Bleyer will contact you for more information and help This is about a student from Pakista...

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RE: Persistant Hemoptysis In Anti-GBM 1 day ago

That provides a good explanation for the recurrence of hemoptysis. He must stop smoking. It could be a life or death decision. -----------------...

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RE: Persistant Hemoptysis In Anti-GBM 1 day ago

Unfortunately patient still active smoker --------------------------------- Mohamed Mahmoud MBBS NEPHROLOGIST MOH Egypt 00965 51377736 -------...

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RE: Persistant Hemoptysis In Anti-GBM 1 day ago

Thank you prof Glassock This patient maintains sat on room air X ray no abnormalities so Ct not done Kidney biopsy with fibrosis so usually the...

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RE: Patient with fabry disease and also possible minimal change 1 day ago

I think I would just pull the trigger on steroids, it has been going on long enough if this were NSAIA related MCD it should have resolved by no...

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RE: Persistant Hemoptysis In Anti-GBM 1 day ago

Pretty classical anti-GBM disease in a young man. A complete return to a normal eGFzr is not expected because of the findings in kidney biopsy. Wha...

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RE: Patient with fabry disease and also possible minimal change 1 day ago

If Proteinuria was from fabry it would be progressive with progressive decline in kidney function..it seems like podocytopathy with background of b...

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RE: Persistant Hemoptysis In Anti-GBM 1 day ago

I forget to mention patient started oral cyclo with plasma exchange after Anti GBM result --------------------------------- Mohamed Mahmoud MBBS ...

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Persistant Hemoptysis In Anti-GBM 1 day ago

23 ye,male no hist of DM or HTN Came with 1 month hist of hampotysis. Cr 267, ur 9.3 Pulmonary renal suspected Anti GBM 68 u/ml Plasma Ex started...

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RE: Patient with fabry disease and also possible minimal change 1 day ago

Complicated case, but I will take the Hickam's Dictum position and opine that she has two diseases- 1) Hemizygous Fabry Disease with rather minor c...

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Patient with fabry disease and also possible minimal change 1 day ago

74-year-old female was referred because of Sudden onset of nephrotic syndrome with swelling of her face lower extremities in 9/2024 had protein 5 g...

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RE: Dialysis Question 1 day ago

Thanks . The water plant unit had an issue and water supply was interrupted After about 90 minutes into dialysis machines stopped due to lack of w...

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RE: Anti Gbm Case 1 day ago

Ea and Eb are two different epitopes on the Goodpasture antigen- COLIValpha3- commercial anti-GBM antibody ELISA do not distinguish between these t...

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RE: Anti Gbm Case 1 day ago

Thanks prof . What is Ea and Eb? --------------------------------- Muhammad Soobadar MBChB UK ---------------------------------

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RE: Thanksgiving 1 day ago

Thank you very much Pr. Glassock. A very happy thanksgiving to you and all the ASN community contributing to this open forum, which I think is real...

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RE: Clinical Practice Questions 1 day ago

In the original description of CMV Glomerulopathy in kidney transplant the findings were enlargement or necrosis of endothelial cells, macrophage i...

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RE: Dialysis Question 1 day ago

I have tested it in a crude fashion over the years and found that K will rebound slightly higher than the other electrolytes over a few hours. Nev...

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RE: diagnostic ability of ChatGPT 1 day ago

Nice reference tool amongst others. Answers are often vague and lack insight. ------------------------------ John Mellas MD Nephrology and Hyper...

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RE: Clinical Practice Questions 1 day ago

Was C4d positive or negative especially Peritubular capillaries ? ------------------------------ [Mark] [Lerman] [MD,FASN,FACP,FAST] AST KPCOP EC...

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RE: Thanksgiving 1 day ago

Many thanks Dr. Reynolds. Much appreciated. Of course, the ASN Communities is the beneficiary of all those who chose to participate. -----------...

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RE: diagnostic ability of ChatGPT 1 day ago

Only six clinical vignettes. Hardly representative of actual practice. Personally, I would not chose to rely on a CHAT-GTP diagnosis (yet)- these L...

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diagnostic ability of ChatGPT 2 days ago

Many of you may be familiar with the recent randomized controlled study comparing ChatGPT diagnostic capabilities compared to attending and residen...

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RE: Clinical Practice Questions 2 days ago

CMV glomerulopathy typically causes endotheliosis with minimal inflammation. CMV can also cause collapsing glomerulopathy, especially in carriers o...

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RE: Thanksgiving 2 days ago

A belated Happy Thanksgicing day and weekend to you, Dr. Glassock, and all! Please know your active involvement in this ASN Community Open Forum...

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RE: Dialysis Question 2 days ago

Assuming you are sampling peripheral venous blood the equilibrium state for elrctrolytes is quite rapid, usually minutes. It is slower for non-elec...

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RE: Clinical Practice Questions 2 days ago

I would wait to see the final report and not speculate at this point. This very well might be AKI secondary CMV Glomerulitis. Can your lab do in si...

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RE: Clinical Practice Questions 2 days ago

The provisional report so far is ATN and possible glomerulitis . More results to come . Dsa negative If there is cellular rejection in this case ...

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Dialysis Question 2 days ago

After how long after haemodialysis can blood test be taken to reflect accurately potassium and other electrolytes ?

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RE: Clot/ Debris In Right Jugular Vein 2 days ago

Photo --------------------------------- Muhammad Soobadar MBChB UK ---------------------------------

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Clot/ Debris In Right Jugular Vein 2 days ago

Dear all this is photo of jugular vein. Patient had a right jugular central line removed Couple of days ago. Right arm not swollen. No hx of dvt o...

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RE: Management In ADTKD 2 days ago

yes, this is a great idea, but biopsies are hard to come by as individuals are undergoing genetic testing. We are actually trying to collect any ol...

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RE: Anti Gbm Case 3 days ago

It can be difficult to predict risk of DAH in anti-GBM disease. Smoking is tge biggest risk, and smoking must be srticjklu forbidden in anyone with...

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RE: Anti Gbm Case 3 days ago

We decreased the dose of cyclophosphamide from 150 mg to 100 mg and Wcc been holding around 6 The team felt a biopsy would be high risk ( increase...

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